STEREOTACTIC RADIOSURGERY FOR BRAIN METASTASES FROM GASTROINTESTINAL PRIMARIES: ANALYSIS OF OUTCOMES

Abstract AIMS Brain metastases from gastrointestinal primaries are uncommon with poor reported outcomes following SRS. We evaluated clinical for patients diagnosed metastatic brain tumours a primary treated stereotactic radiosurgery (SRS). METHOD A single institutional retrospective review of LINAC-based SRS at our institution between 2017 and 2022. Median survival was calculated the time RESULTS total 24 were malignancy locations as follows: 10 colon, 7 rectum oesophageal. 6.4 months overall cohort 4.5 6.1 14 oesophagus. 44% 14% had undergone surgical resection colorectal cancer (CRC) oesophageal respectively. in CRC receiving post-operatively 6.8 compared 11.5 non-gastrointestinal primaries. Time diagnosis to showed an inverse correlation survival: 48 21 13 Compared patients, more likely have extra-cranial disease (57% vs. 18%). CONCLUSIONS Survival after is poor, but we demonstrate important differences outcome depending on location malignancy. Oesophageal best colon having worst. Although findings influenced by patient selection bias, these worthy further investigation.